Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial. Menopause: The Journal of The North American Menopause Society. The 2022 hormone therapy position statement of The North American Menopause Society. Hormone therapy, dementia, and cognition: the Women’s Health Initiative ten years on. Journal of the American Medical Association. Association of the menopausal hormone therapy with breast cancer incidence with mortality during long-term follow-up of Women’s Health Initiative clinical trials. Sleep and sleep disorders in the menopausal transition. We’ll discuss 11 of the most notable side effects below. Like most medications, Premarin has some side effects you should be aware of. A personal lubricant or vaginal estrogen are the first choice for these types of menopause symptoms. If you only have vaginal symptoms, Premarin tablets aren’t typically recommended. This is to prevent extra growth of the tissue lining the uterus. If you still have a uterus, you will also need to take a second medication - a progestin - with Premarin. This can help relieve moderate to severe symptoms of menopause, like hot flashes and night sweats. HRT replaces hormones, such as estrogen, that your body makes less of as a result of menopause. Premarin is most often used as hormone replacement therapy (HRT). Premarin (conjugated estrogens) is a combination of different estrogens made from an animal source - the urine of pregnant horses. As estrogen levels go down, you may experience hot flashes, night sweats, and bothersome vaginal symptoms. Menopause is the time of life for women when estrogen levels fall and your periods stop for good.
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